Laboratory Members

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Craig Lowe
Principal Investigator

Craig's background is in computer science, bioinformatics, and developmental genetics, which spans both computational and experimental research. He is a new faculty member in Molecular Genetics and Microbiology, as of June 2018, and is actively recruiting graduate students with interests in better understanding vertebrate animals, how they adapt, and their genetic risk/protection from disease.

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Riley Mangan
Graduate Student

Riley is a graduate student through the Cell and Molecular Biology (CMB) Program and a graduate of Davidson College. Riley is interested in combining tools from evolutionary biology, comparative genomics, and developmental neuroscience to answer questions about human-unique evolutionary processes and disease mechanisms.

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Christiana Fauci
Graduate Student

Christi is a graduate student in the University Program in Genetics and Genomics (UPGG). The chicken has a rich history of being used as a model organism in developmental biology and was one of the first vertebrate genomes to be sequenced. It has advantages over other organisms, such as sharing many aspects of human development, yet developing outside the mother where it can be continually imaged. However, since the chicken genome was published in 2004, development of genetic and genomic techniques have not kept pace with other model organisms. Christi is working hard to change this and have molecular techniques in the chick once again be on the leading edge of biology.

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Luke Bartelt
Graduate Student

Luke is a graduate student in the University Program in Genetics and Genomics (UPGG). He is jointly advised by Craig and Al La Spada (UC Irvine). Luke is interested in understanding the molecular mechanisms that connect poly-Q expansions to neurodegeneration, with a focus on Spinocerebellar Ataxia Type 7. Luke is using new genomic techniques to analyze these diseases at the level of single cells.

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Juliana Carvalho
Staff Researcher

Juliana is interested in understanding the genetic basis of brain expansion and cognative abilities cross a wide variety of mammals. She has a background in both anthropology and marine biology. Her research combines genomics, neurobiology, and the fossil record.

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Chelsea Shoben
Graduate Student

Chelsea is a graduate student in the University Program in Genetics and Genomics (UPGG). She is interested in better understanding the most repetitive and difficult-to-analyze regions of the genome. Chelsea is currently focused on understanding the functional consequenes of variation within human populations that has only recently become possible to analyze.

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Graduate Student

We are looking for new graduate students to join us who share an interest in the genetics of vertebrates. Students may have backgrounds in the life sciences, engineering, mathematics, or any other field of study; we value having people with diverse backgrounds and unique perspectives. The lab is affiliated with the: MGM, DSCB, UPE, CMB, CBB, and UPGG graduate programs. If you are interested, please contact Craig or stop by lab to talk.

Former Lab Members

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Eric Au
Staff Researcher

Eric's background is in applied mathmatics, but when he joined our lab he also had over five years of experience with stickleback fish and had worked in Stanford's Genome Center for a year. Eric worked on new computational frameworks for representing genetic variation within a species. Eric now works at Invitae where he is developing new methods to efficiently analyze human genomes for medically relevant mutations.